Peptide stacks
Stacking refers to the practice of combining multiple peptides in a single research protocol to target complementary biological pathways. This page provides an overview of common stacking rationale and highlights frequently researched combinations.
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Featured combinations
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Peptides in catalog
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Research use only
Research use only. All information on this page refers to preclinical research models. Peptide stacking protocols described here are for laboratory and analytical purposes only and do not constitute medical advice. Products are not approved for human use.
What is peptide stacking?
Peptide stacking is the simultaneous or sequential use of multiple peptide compounds within a single research protocol. Each peptide in a stack typically targets a different receptor system or biological pathway, allowing researchers to study multi-pathway interactions that would not be visible when testing compounds in isolation.
Stacks are designed around research goals. A recovery-focused stack might combine BPC-157 with TB-500 to study joint and tissue repair, while a metabolic stack might pair a GLP-1 agonist with a selective lipolytic compound to examine complementary fat-burning mechanisms.
Full stack combinations for each compound are listed on individual product pages, including background on why specific pairings are studied together.
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Synergistic pathways
Different peptides target distinct biological mechanisms. Combining them allows researchers to activate multiple pathways simultaneously, potentially producing results that neither compound achieves alone.
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Protocol flexibility
Stacking allows researchers to tailor protocols to specific research goals — whether that's tissue repair, metabolic support, cognitive function, or hormonal modulation.
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Complementary mechanisms
Many peptides work through separate but complementary receptor systems. Pairing them can broaden the scope of a study while keeping individual dosages within the ranges used in preclinical models.
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Established in literature
Peptide combinations such as BPC-157 + TB-500 and CJC-1295 + Ipamorelin are among the most cited multi-compound protocols in preclinical research, providing a foundation for further investigation.
Frequently researched stacks
The combinations below represent some of the most frequently cited multi-peptide protocols in preclinical literature. Visit each product page for the full list of stack options specific to that compound.
Tissue repair & recovery
The most widely researched peptide combination in regenerative medicine. BPC-157 supports angiogenesis and gut-gut axis signaling while TB-500 promotes actin polymerization and cell migration. Together they are studied for accelerated injury recovery, tendon/ligament repair, and anti-inflammatory effects.
Research areas
Cycling:8–12 week cycles with 4-week rest periods are most common in preclinical models.
Tissue repair + skin regeneration
An extended repair stack adding GHK-Cu for collagen stimulation, antioxidant signaling, and skin remodeling. GHK-Cu is studied for its role in wound healing, skin barrier restoration, and anti-aging pathways — a natural complement to the BPC-157/TB-500 core.
Research areas
Cycling:GHK-Cu can typically be run longer than peptide injections — topical applications are often cycled separately.
Metabolic & fat loss
A multi-target metabolic stack combining GLP-1 receptor agonism (Semaglutide), NNMT inhibition for NAD⁺ and fat oxidation enhancement (5-Amino-1MQ), and selective lipolysis stimulation (AOD-9604). Investigated in obesity and body composition research models.
Research areas
Cycling:Cycles of 8–16 weeks are typical, with monitoring for metabolic markers at regular intervals.
Growth hormone stimulation
One of the most commonly referenced GH-releasing peptide combinations in research. CJC-1295 extends the half-life of GHRH, while Ipamorelin selectively triggers GH release without significant cortisol or prolactin elevation. Together they are studied for muscle preservation, fat metabolism, and recovery in aging models.
Research areas
Cycling:12–16 week cycles are standard; some protocols use 5 days on / 2 days off to maintain pulsatile GH patterns.
Cognitive & neuroprotection
A nootropic combination investigated for its effects on BDNF expression, anxiety reduction, and neurogenesis. Selank has anxiolytic properties through GABAergic modulation, while Semax promotes ACTH and BDNF signaling. Research suggests complementary effects on focus, learning, and stress resilience.
Research areas
Cycling:Nasal peptide cycles are often shorter — 2–4 week protocols with breaks are common in research settings.
Skin quality & hair growth
A dermatological stack combining copper peptides and anti-inflammatory KPV. GHK-Cu stimulates collagen and wound repair, AHK-Cu activates hair follicle cycling and scalp circulation, and KPV reduces skin inflammation and supports barrier function. Widely explored in topical and aesthetic research.
Research areas
Cycling:Topical applications are typically continuous over 8–16 weeks with photographic and histological assessment.
More combinations on each product page
The stacks shown here are just a starting point. Every product in the Myotrope catalog includes its own dedicated stacks section with peptide-specific combination rationale, pairing descriptions, and cycling notes drawn from preclinical research.
Questions about stacking?
Our team can help with technical questions about peptide combinations and research protocols.